To evaluate the applicability and reproducibility of CoRec, we performed experiments for the COFs P300 (acetyltransferase), BRD4 (scaffold protein) and TBL1XR1 (subunit of NCOR/SMRT repressor complexes) using extracts from three different cell lines: HEK293 (embryonic adrenal precursor cells) (52), Jurkat (T-cell leukemia cells) and SUDHL4 (B-cell lymphoma cells). Here, TBL1XR1 is linked to B-cell non-Hodgkin lymphoma.