Consistently, the activation of the Akt/mTOR pathway decreased with ALO treatment in NSCLC cells in vitro and mouse tumor models in vivo, whereas the levels of Beclin‐1 and ATG7 increased (Figure S6, Supporting Information), indicating that ALO may promote autophagosome formation by interfering with the Akt/mTOR pathway. Here, BECN1 is linked to non-small cell lung carcinoma.