VEGFA and preeclampsia: The pathogenic mechanisms include failure of spiral artery remodeling (Staff et al., 2022), imbalance of vascular endothelial growth factor and sFlt1 (Vieillefosse et al., 2016), placental oxidative stress (Guerby et al., 2021), immune dysregulation (Wang et al., 2013), and progressive deterioration that can only be cured by delivery (Gestational Hypertension and Preeclampsia, 2020).