Even though the RNA levels of Hspb1, Eef1b2, Hmgb1, Hnrnpa1, Rps7 (ribosomal protein S7), Rps21 (ribosomal protein S21), and Hnrnpk (heterogenous nuclear ribonucleoprotein K) did not correlate with protein levels, JL-DCIS-3 was consistent with the invasive breast cancer pattern (all stages) in the mRNA expression of these genes (Figure 5). The gene discussed is HMGB1; the disease is invasive breast carcinoma.