Clinical and imaging factors, including age, gender, AFP, serum total bilirubin, total plasma protein, prothrombin time, blood platelet levels, tumor size, non-rim arterial phase hyperenhancement (APHE), non-peripheral washout, enhancing and non-enhancing capsule, necrosis, satellite lesions, and internal arteries, were analyzed using the stepwise regression forward method to select the significant independent predictors in the training cohort. This evidence concerns the gene AFP and neoplasm.