CD4 and diabetic kidney disease: Our study also revealed that diabetic kidney disease (DKD) is associated with decreased levels of CD27 on memory B cells (OR=0.91, 95% CI=0.86-0.97, p=0.006) and SSC−A on CD4+ cells (OR=0.81, 95% CI=0.73-0.91, p<0.001) (Figure 2).