KMT2C and medulloblastoma: study, KMT2C was one of the most commonly mutated genes, with 30% of mutations detected in cases of different ages, sexes, histological types, and molecular typologies, again demonstrating the central importance of chromatin modifications in the pathophysiology of medulloblastomas (130) and highlighting the fact that a more comprehensive review of the adult medulloblastoma epigenetic landscape is the need for a more comprehensive assessment (131).