S100A8 and Tremor: Under the stringent significant threshold (Table 2 and Supplementary Table 4), genetically predicted HP CagA antibody level was negatively associated with the tremor/PIGD score ratio using the IVW method (β = -0.162; Standard Error (SE) = 0.05; P = 0.002) and the weighted median method (β = -0.191; SE = 0.07; P = 0.007).