The peak tension during contractions (Fig. 2G) did not change following insulin microinjections in T2DM rats (Pre: 834 ± 298 g, 1 h: 701 ± 369 g, 2 h: 571 ± 352 g in control vs. Pre: 975 ± 292 g, 1 h: 960 ± 429 g, 2 h: 900 ± 424 g in T2DM). Here, INS is linked to type 2 diabetes mellitus.