TP53 and non-small cell lung carcinoma: Therefore, we performed stratification analyses for the prognostic effects of FOSB expression based on a series of genetic molecular markers in both LUAD and LUSC as an attempt to identify the underlying critical determinants that contribute to the contradictory prognostic effects of FOSB in NSCLC (Data not shown).Notably, the TP53 gene stood out for its remarkable disparity in the mutation frequency between LUAD and LUSC, which was approximately 50% in LUAD versus over 85% in LUSC (Fig. 2A).