TP53 and neoplasm: For each group, we analysed TP53 status wild-type (wt-TP53) or mutated, and the prevalence of BCs histotypes (Normal-like, Basal-like, HER-2, luminal-A, luminal-B) as a measurement of tumor malignancies (Pie-charts Fig. 1A, B, Fig. S1A, B).