Gliomas frequently exhibited concurrent aberrations in these pathways, with glioblastoma having an average of 2.8 pathways affected (median: 3), IDH1/2-mutant astrocytoma with 1.7 (median: 1), and oligodendroglioma with 1.5 (median: 1, Supplementary Material 4). The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).