Although no significant differences between groups were observed in immune cell numbers or production of IFNγ, IL-17A and IL-22 in the lamina propria when analyzed by flow cytometry (Figure S3), histological analysis revealed increased colitis scores in the ethanol group, with an overall increase in the majority of the disease parameters analyzed (epithelial injury, epithelial crypt hyperplasia, and mononuclear cell infiltration; weighted for the extent of disease) (Figure 4(h,i)). Here, IL22 is linked to colitis.