The results showed that the mRNA expression levels of METTL3 and ADARB1 were both significantly higher in HCC tissues than in normal tissues (p = 1.6 × 10−12 and 2.0 × 10−15, respectively; Figure 4A,D), similar results were found in our RNA‐Seq data for the mRNA expression levels of METTL3 (p = 2.2 × 10−16, Figure 4B) and ADARB1 (p = 0.03341, Figure 4E). This evidence concerns the gene METTL3 and hepatocellular carcinoma.