APOL3 and chronic kidney disease: We replicated this observed association between the APOL3 p.Q58* variant and CKD/ESRD using identical methods in the AFR population in the Million Veteran Program (MVP) (n = 120,839) and found an OR of 1.16 (95% CI = 1.10–1.22, P = 1.01 × 10–8).