To isolate the independent effects of the 3 significant non-APOL1 G1/G2 variants on renal disease, we assessed conditional associations for the 3 variants in the PMBB AFR population for all phenotypes originally found to be significantly associated during assessment of conditioning for APOL1 G1/G2, which was risk modeled using APOL’s well-known recessive inheritance pattern (Table 2). The gene discussed is APOL1; the disease is kidney disorder.