Themultivariable model did not include SUVmax in the SOC only arm.Whole-body tumor SUVmean was associated with improved odds of aconfirmed PSA response in the 177Lu-PSMA-617 plus SOC arm (OR, 1.23[95% CI: 1.16, 1.31]; P < .001) (Fig 3, TableS2) in the final treatment-adjustedmultivariable model. This evidence concerns the gene KLK3 and neoplasm.