In agreement with this cross-sectional study, a case-control study performed by Zhong et al. [73] found that patients with T2DM and coronary artery disease had significantly low serum Nrg4 levels which negatively correlated with a history of hypertension, BMI, FPG, HbA1c, TG, and TG-glucose, and positively correlated with HDL-c. Here, NRG4 is linked to coronary artery disorder.