The results revealed that the best cut-off value for circulating asprosin to predict CAD was 19.0 ng/ml (sensitivity: 66.2%, specificity: 71.2%, and AUC 0.671), and the best cut-off value for circulating Nrg-4 to predict CAD was 11.175 ng/ml (sensitivity: 67.5%, specificity: 75%, and AUC 0.772) [73]. Here, FBN1 is linked to coronary artery disorder.