ACTA1 and renal fibrosis: We also examined the effect of GJ103 in the UIRI model, and consistent with the results obtained in the UUO model, GJ103 (30 mg kg−1 day−1) also improved UIRI‐induced renal fibrosis, manifested in improved Masson's trichrome and Picrosirus Red staining (Figure 8J,K), reduced extracellular matrix deposition (Figure 8L,M), and alleviated α‐SMA expression (Figure 8N,O).