Compared to UUO and UIRI models, which lack functional readouts, renal function in the FA model can be assessed as a measure of CKD.[22] As shown in Figure 2R,S, there were no significant differences in serum creatinine (Scr) or blood urea nitrogen (BUN) levels between the WT and Meis1‐cKI mice at baseline. This evidence concerns the gene CHKA and chronic kidney disease.