Despite those similarities, some degree of heterogeneity was observed between the ACC cell lines and the ACC surgical samples with respect to steroidogenesis (Fig. 2A), ABC transporter expression (Fig. 2B), TERT expression (Fig. 5), MGMT expression, MMR status (Fig. 8), and SLFN11 expression (Supplementary Fig. S4). This evidence concerns the gene ABCG2 and adrenal cortex carcinoma.