Dysregulation of GJIC is directly associated with oncogenesis.[13] In various malignancies affecting the breast, colon, lung, and cervical regions, abnormal expression of the GJB2 gene disrupts GJIC.[14, 15] A comprehensive pan‐cancer study conducted by Yuting Jia and colleagues[16] explored the potential significance of GJB2 in prognostic prediction and cancer immunotherapy response. Here, GJB2 is linked to cancer.