,84,85 Our analysis of NSCLC spatial transcriptomics, despite being limited by the current data availability, confirmed the high abundance and geospatial heterogeneity of fibroblasts and myeloid cells, and confirmed peribronchial fibroblasts and classical monocytes as the major sources of TGFβ and TNFα/NF-κB pathway activity, respectively. The gene discussed is TNF; the disease is non-small cell lung carcinoma.