,84,85 Our analysis of NSCLC spatial transcriptomics, despite being limited by the current data availability, confirmed the high abundance and geospatial heterogeneity of fibroblasts and myeloid cells, and confirmed peribronchial fibroblasts and classical monocytes as the major sources of TGFβ and TNFα/NF-κB pathway activity, respectively. Here, TGFB1 is linked to non-small cell lung carcinoma.