The Kaplan-Meier plotter analysis of a publicly available database (http://kmplot.com) (Gyorffy, 2021; Lanczky and Gyorffy, 2021) also showed that high Cyclin D1 or CDK4 expression predicted dismal overall survival (OS) as well as relapse-free survival (RFS) in BC cases (Figures 5H, I). This evidence concerns the gene CDK4 and breast cancer.