TP53 LOF is often correlated with nonautonomous effects on the tumor immune microenvironment; it subverts the wt p53 effect and allows the evasion of attack from the immune system (Prokocimer et al., 2017; Loizou et al., 2019; Hassin and Oren, 2023; Rajagopalan et al., 2023). Here, TP53 is linked to neoplasm.