The GTH-AH 01/2010 study reported that complete remission (CR) of AHA was associated with baseline FVIII : C < 1% and World Health Organization (WHO) performance status > 2, whereas survival of AHA was associated with FVIII : C < 1%, WHO performance status > 2, and malignancy [42]. The gene discussed is F8; the disease is autoimmune hemolytic anemia.