PIK3CG and hepatocellular carcinoma: Further experiments involving MHCC-97L and Hep3B cells clarified that DUXAP10 overexpression triggers G-protein–coupled receptor 39 (GPR39) expression and PI3K/AKT signaling, intensifying HCC malignant processes including cell proliferation, colony formation, cell cycle progression, and antiapoptosis (Sun et al., 2019).