Other fusion proteins with NUP moieties, such as SET-NUP214, SQSTM1-NUP214, NUP98-HOXA9, NUP98-DDX10, and NUP98-IQCG have also been shown to interact with CRM1, suggesting the importance of the NUP-CRM1 interaction in these leukemias [33–36]. The gene discussed is NUP214; the disease is leukemia.