N = 161 patientsORR: 15% ( CR 5 patients, PR 16 patients)DOR: 15.4 mORR rate by PD-L1 status• Positive (n = 85) : ORR 20.0%• Negative (n = 38): ORR 7.9 %• Unknown (n = 17): ORR 5.9%Objective response rate by histology• Squamous (n = 85) ORR 17.6%• Adenocarcinoma (n = 48): ORR 12.5% The gene discussed is CD274; the disease is adenocarcinoma.