KLRK1 and neoplasm: Additionally, interesting results were obtained in non-small cell lung cancer (NSCLC) cell line NCI-H23 cells, where ionizing radiation and HDAC inhibitors (Apicidin, SAHA, or TSA) in combination synergistically increased both the expressions of NKG2D ligands and sensitivity of NSCLC cell line to NK cells-NK-92, enhancing tumor eardication (24).