PECAM1 and neoplasm: This observation was further confirmed by TUNEL assay, which showed that bevacizumab induced apoptosis in both tumour cells and vascular endothelial cells, while in the AEFs group, most apoptotic cells (green) overlapped with the CD31‐labelled vascular endothelial cells (Red) (Figure 5A), implying that 1000 kHz AEFs preferentially induce apoptosis of vascular endothelial cells rather than the tumour cells.