Furthermore, we found that GATM might mainly contribute to xenobiotic metabolism, MYC targeting, and epithelial mesenchymal transition among cancers, while MGST1 participated in xenobiotic metabolism, TNFa signalling, the reactive oxygen species pathway, oxidative phosphorylation, interferon, the G2/M checkpoint, and epithelial mesenchymal transition in cancers (Figure 8D,E). Here, TNF is linked to cancer.