Given that IL‐6 plays a direct role in driving cardiovascular disease events related to chronic inflammation of RA, in the following, for the first time, the correlation between the plasma level of IL‐6 with components and scores obtained from CVD risk prediction algorithms, SCORE and FRS, and well established cardiac biomarker NT‐proBNP, and HS‐CRP was evaluated in RA patients.41 This evidence concerns the gene IL6 and rheumatoid arthritis.