VHL and Miyoshi myopathy: Moreover, VHL (Supplemental Fig. 4a) and BRD4 (Supplemental Fig. 4b) are highly expressed across all malignant lymphoid cell lines, including MM cells (Supplemental Fig. 4a–d), and do neither carry any VHL nor BRD4 hotspot or loss of function mutation (Supplemental Fig. 4e–h).