Extensive literature underscores the nexus between thyroid hormones and progression of cardiovascular ailments, such as the independent predictive value of hypothyroidism or low T3 syndrome for cardiovascular adverse events and/or death in AMI patients (5, 32), the relationship between thyroid function and risk of atrial fibrillation and stroke (33), and the relationship between thyroid function and incidence and mortality of atherosclerotic cardiovascular disease (34). The gene discussed is TG; the disease is atrial fibrillation.