Assessing six HDME lots differing in total protein, antigen, and endotoxin contents, Cyphert-Daly et al. (42) reported that Der p 1 concentration in the HDME correlates with lung IL-5 and eosinophilia, serum IgE as well total protein in bronchoalveolar lavage (BAL) fluid. Here, IL5 is linked to Increased total eosinophil count.