GBM-induced M2-like macrophages showed increased secretion of anti-inflammatory cytokines TGF- β one and IL-10, which promoted capillaries, proliferation, and angiogenesis sprouting of vascular endothelial cells, while classic activated M1-like macrophages inhibited angiogenic activity (Cui et al., 2018). Here, IL10 is linked to glioblastoma.