Basit et al. excluded the currently known variation of DDH-related genes (ASPN,CX3CR1, DKK1, GDF5, HOXB9, HOXD9, PAPPA2,TGFβ1) in five members of a Saudi family (including three DDH patients) using WES and found common haplotypes of HSPG2 and ATP2B4 gene variants on chromosome 1 with incomplete penetrance. The gene discussed is ASPN; the disease is Hip dysplasia.