Cheng et al. compared the hip cartilage of DDH patients and control cases by whole transcriptome sequencing and identified 186 differential miRNA-targeted 175 DDH candidate genes from 1833 differential mRNAs, such as von Willebrand factor A domain containing 1, transmembrane protein 119 and signal peptide, CUB domain and EGF like domain containing 3. The gene discussed is VWA1; the disease is Hip dysplasia.