Although a case-control study of a Caucasian population (239 cases and 239 controls) from western Brittany, France, showed no association between multiple SNPs of HOXB9 and DDH (Rouault et al., 2009), a subsequent study showed that DNA extraction from a multi-generation DDH family of 18 members revealed that a 4 Mb region abnormality on chromosome 17q21.32, which contains the entire HOXB homologous gene cluster, may be associated with DDH and was confirmed to be inherited in an autosomal dominant manner (Feldman et al., 2010). This evidence concerns the gene HOXB9 and Hip dysplasia.