Among these lncRNAs, 12 epi-lncRNAs were selected for further analysis for their role in ccRCC previously reported, including HOTAIR, HOTTIP, HOXA11-AS, LINC00461, LUCAT1, PVT1, XIST, H19, HCP5, LINC00160, MIAT and GAS6-AS1. The gene discussed is HOTTIP; the disease is nonpapillary renal cell carcinoma.