SIN3A and Autoimmunity: However, unlike in Sin3a−/−FoxP3cre, the percentages (Supplementary Figure S4A) and numbers (Supplementary Figure S4G) of CD4+ and CD8+ T cells in the SLOs of Sin3a−/−CD4cre mice were greatly reduced, providing an explanation as to why these mice do not develop fatal autoimmunity.