AKT1 and cancer: Additionally, Kyoto Encyclopedia of Genes and Genomes analysis revealed the complex and extensive involvement of MSC-related genes in various regulatory pathways, including extracellular matrix–receptor interaction, protein digestion and absorption, focal adhesion, the PI3K–Akt signaling pathway, proteoglycans in cancer, human papillomavirus infection, the TGF-β signaling pathway, amoebiasis, and age-related signaling pathways.