To determine the effect of ART on the liver, kidney and heart functions after hypothyroidism in rats, the serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), urea, creatinine, lactate dehydrogenase (LDH), creatine kinase MB (CK-MB) activities were determined. This evidence concerns the gene GPT and hypothyroidism.