The 5-ethynyl-2′-deoxyuridine (EdU) results showed that MTA1 knockdown or MTA3 overexpression caused a significant decrease in EdU-labeled breast cancer cells, and MTA1 overexpression or MTA3 knockdown caused the opposite effect (Fig. 1G and Supplementary Fig. 1D, E). The gene discussed is MTA1; the disease is breast carcinoma.