Apart from its impacts on cellular apoptosis, Dex also played a role in cellular proptosis in neuroprotection, which has been shown to reduce early brain injury in rats with subarachnoid hemorrhage by inhibiting the activation of TLR4/NF-κB(TLR4, toll-like receptor 4; NF-κB, nuclear factor-kappa B) pathway and attenuating eosinophilic prolapse of microglia [60]. This evidence concerns the gene TLR4 and subarachnoid hemorrhage.