Since HLA-A*01:01-B*08:01-C*07:01-DQB1*02:01- DRB1*03:01 is the most common HLA-A-B-C-DQB1-DRB1 haplotype in Europeans (AF = 0.074) [77], comprehensive analysis of the HLA haplotypes and their contribution to the risk of PSP is needed in the future. The gene discussed is HLA-DRB1; the disease is supranuclear palsy, progressive, 1.