The CDH1 gene is involved in regulating cell adhesion, migration, and epithelial cell proliferation, and its loss of function makes it easier for cells to invade and metastasize.[45,46] Mutations in CDH1 are closely related to ovarian cancer, thyroid cancer, colorectal cancer, BC, and gastric cancer.[47–51]. The gene discussed is CDH1; the disease is thyroid gland carcinoma.