Specifically related to the atherosclerotic process, the ATHEROREMO‐IVUS (European Collaborative Project on Inflammation and Vascular Wall Remodelling in Atherosclerosis – Intravascular Ultrasound) study suggested a direct role of PCSK9 on the atherosclerotic plaque formation, independent of the LDLc lowering effect. Here, PCSK9 is linked to atherosclerosis.