Testing previously evaluated parameters and indices (Supplementary Table S1; ref, 48), a significant impact on survival in the current cohort was identified by univariate Cox regression for age (HR: 1.06; P = 0.015), subsequent radiotherapy (HR: 0.27; P = 0.024) and chemotherapy (HR: 0.31; P = 0.003) as well as TSPO-PET signal of the tumor (HR: 1.85; P = 0.024), T1 contrast enhanced volumes (HR: 1.03; P < 0.001) and T2 hyperintensity volumes (HR: 1.02; P < 0.001). Here, TSPO is linked to neoplasm.