Previous studies have reported some clinical and genetic differences between adults (>18 years of age) and patients diagnosed in childhood; however, studies comparing adults with late-onset patients remain quite limited.6-8 In our study, we aimed to evaluate the sociodemographic characteristics, clinical findings, and MEFV mutation analysis results of patients aged 18 years and older diagnosed with FMF in our center. This evidence concerns the gene MEFV and familial Mediterranean fever.