Our observations suggested that androgen treatment induced YAP and N‐cadherin while suppressed E‐cadherin, at least partially, via regulation of hsa‐miR‐203a, hsa‐miR‐210‐3p, and hsa‐miR‐5001‐5p in AR‐positive PCa cells. Here, YAP1 is linked to posterior cortical atrophy.