CXCL9 and isolated hyperferritinemia: Labs typically demonstrate cytopenia of at least two lineages, hyponatremia, elevated liver function tests, renal dysfunction, bleeding diathesis, hyperferritinemia, hypertriglyceridemia, and hypofibrogenemia [6]. Cytokines that are found at extremely high levels in HLH are chemokine ligand 9 (CXCL9), interleukins (ILs) 1, 6, 10, and 12, and soluble IL-2 receptors [7].