The diagnosis of A-T is generally based on a clinical triad characterized by neurological symptoms, notably a progressive static cerebellar syndrome, oculocutaneous manifestations such as telangiectasias or café-au-lait spots, and an immune deficiency involving both humoral and cellular components, leading to recurrent respiratory and pulmonary tract infections, with increased serum levels of alpha-fetoprotein [6]. This evidence concerns the gene AFP and Immunodeficiency.